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March 31, 2023
DOI:
1School of Biomedical Sciences, Faculty of Medicine,The Chinese University of Hong Kong, 2Institute for Tissue Engineering and Regenerative Medicine,The Chinese University of Hong Kong, 3Center for Neuromusculoskeletal Restorative Medicine,The Chinese University of Hong Kong, 4Key Laboratory for Regenerative Medicine, Ministry of Education, School of Biomedical Sciences,The Chinese University of Hong Kong, 5Department of Orthopaedics and Traumatology, Faculty of Medicine,The Chinese University of Hong Kong
Summary
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Este estudo detalha os procedimentos para o estabelecimento de uma lesão crônica do manguito rotador (MR) de coelhos. Especificamente, a lesão é criada na unidade músculo-tendão/miotendíneo subescapular (SSC) para mimetizar a anatomia e fisiopatologia do MR humano, incluindo degeneração gordurosa muscular (DF) grave. Este protocolo pode ser aplicado para estudar lesões do MR e avaliar terapias regenerativas.
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Li, K., Zhang, X., Wang, D., Ker, D. F. E. Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration. J. Vis. Exp. (193), e64828, doi:10.3791/64828 (2023).
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