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Biology

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Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
 

Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration

Article DOI: 10.3791/64828-v 05:20 min March 31st, 2023
March 31st, 2023

챕터

요약

This study details procedures for establishing a chronic-like rabbit rotator cuff (RC) injury. Specifically, the injury is created in the subscapularis (SSC) muscle-tendon/myotendinous unit to mimic human RC anatomy and pathophysiology, including severe muscle fatty degeneration (FD). This protocol can be applied to study RC injuries and assess regenerative therapies.

Tags

Keywords: Rabbit Rotator Cuff Chronic Injury Fibrosis Fatty Degeneration Subscapularis Tendon Transection Animal Model Surgical Technique Histology
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