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Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
JoVE 杂志
生物学
This content is Free Access.
JoVE 杂志 生物学
Development of a Rabbit Chronic-Like Rotator Cuff Injury Model for Study of Fibrosis and Muscular Fatty Degeneration
DOI:

05:20 min

March 31, 2023

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Chapters

  • 00:04Introduction
  • 01:01Surgical Procedure
  • 03:20Results: Histological Analysis of Chronic‐Like Rotator Cuff Injury Model
  • 04:25Conclusion

Summary

自动翻译

This study details procedures for establishing a chronic-like rabbit rotator cuff (RC) injury. Specifically, the injury is created in the subscapularis (SSC) muscle-tendon/myotendinous unit to mimic human RC anatomy and pathophysiology, including severe muscle fatty degeneration (FD). This protocol can be applied to study RC injuries and assess regenerative therapies.

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