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軽度外傷性脳損傷の覚醒閉鎖頭部損傷モデルを用いたシナプス可塑性変化の評価
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Neuroscience
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JoVE Journal Neuroscience
Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
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軽度外傷性脳損傷の覚醒閉鎖頭部損傷モデルを用いたシナプス可塑性変化の評価

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09:49 min

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January 20, 2023

DOI:

10.3791/64592-v

DOI:
10.3791/64592-v

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09:49 min
January 20, 2023

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1Division of Medical Sciences,University of Victoria, 2Island Medical Program,University of British Columbia

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Synaptic PlasticityAwake Closed-head Injury ModelMild Traumatic Brain Injury (mTBI)Transverse Hippocampal SlicesNeurological Assessment Protocol (NAP)Electrophysiological RecordingsBrain DissectionSlice Preparation

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Christie, B. R., Gross, A., Willoughby, A., Grafe, E., Brand, J., Bosdachin, E., Reid, H. M. O., Acosta, C., Eyolfson, E. Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury. J. Vis. Exp. (191), e64592, doi:10.3791/64592 (2023).

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