/
/
Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Zum Anzeigen dieser Inhalte ist ein JoVE-Abonnement erforderlich. Melden Sie sich an oder starten Sie Ihre kostenlose Testversion.
Assessing Changes in Synaptic Plasticity Using an Awake Closed-Head Injury Model of Mild Traumatic Brain Injury
Kapitel
- 00:04Introduction
- 01:01Induction of Mild Traumatic Brain Injuries (mTBI)
- 02:10Slice Preparation
- 04:09Field Electrophysiology
- 07:36Results: Effects of Repeated Mild Traumatic Brain Injury (r-mTBI) on Synaptic Plasticity in the Hippocampus
- 09:02Conclusion
Here, it is demonstrated how an awake closed-head injury model can be used for examining the effects of repeated mild traumatic brain injury (r-mTBI) on synaptic plasticity in the hippocampus. The model replicates important features of r-mTBI in patients and is used in conjunction with in vitro electrophysiology.
