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Immunology and Infection
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Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules
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Immunology and Infection
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JoVE Journal Immunology and Infection
Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules

Zebrafish Animal Model for the Study of Allergic Reactions in Response to Tick Saliva Biomolecules

DOI:
10.3791/64378-v

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07:01 min

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September 16, 2022

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, ,
1SaBio. Instituto de Investigación en Recursos Cinegéticos IREC (CSIC-UCLM-JCCM), 2Department of Veterinary Pathobiology, College of Veterinary Medicine,Oklahoma State University

Chapters

  • 00:04Introduction
  • 01:04Zebrafish Treatment and Ixodes ricinus Tick Saliva Extraction
  • 02:11Maintenance of Zebrafish, Injection, and Feeding
  • 03:28Sample Collection
  • 04:58Results: Evaluating Tick-Borne Allergies and Alpha-Gal Syndrome
  • 06:16Conclusion

Summary

Automatic Translation

Automatic Translation

Here, zebrafish (Danio rerio) is used as a model to study allergic reactions and immune responses related to alpha-Gal syndrome (AGS) by evaluating allergic reactions to tick saliva and mammalian meat consumption.

Tags

ZebrafishAnimal ModelAllergic ReactionsTick SalivaBiomoleculesAlpha-Gal SyndromeImmune MechanismsTick-host InteractionSaliva ExtractionProtein ConcentrationIntradermal InjectionAnesthesiaRecovery

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