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Fluorimetria a scansione nano-differenziale per lo screening nella scoperta di piombo basata su frammenti

JoVE Journal
Biochemistry

This content is Free Access.

JoVE Journal Biochemistry

Nano-Differential Scanning Fluorimetry for Screening in Fragment-based Lead Discovery

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Fluorimetria a scansione nano-differenziale per lo screening nella scoperta di piombo basata su frammenti

4,203 Views

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06:26 min

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May 16, 2021

DOI:

10.3791/62469-v

DOI:

10.3791/62469-v

•

06:26 min

May 16, 2021

•

4 Views

Misbha Ud Din Ahmad, Alexander Fish, Jeroen Molenaar, Sridhar Sreeramulu, Christian Richter, Nadide Altincekic, Harald Schwalbe, Hans Wienk, Anastassis Perrakis

¹Oncode Institute and Division of Biochemistry,the Netherlands Cancer Institute, ²Institute for Organic Chemistry and Chemical Biology, Center for Biomolecular Magnetic Resonance (BMRZ),Johann Wolfgang Goethe-University

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