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3D Modeling of Dendritic Spines with Synaptic Plasticity
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Neuroscience
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JoVE Journal Neuroscience
3D Modeling of Dendritic Spines with Synaptic Plasticity

3D Modeling of Dendritic Spines with Synaptic Plasticity

DOI:
10.3791/60896-v

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07:13 min

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May 18, 2020

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1Center for Mathematics, Computation and Cognition,Federal University of ABC

Chapters

  • 00:04Introduction
  • 00:39Single Dendrite Spine Creation
  • 02:47Multiple Spine Dendrite Creation
  • 03:57Molecule Creation and Model Output Planning
  • 04:41Simulation
  • 05:42Results: Representative 3D Dendritic Spine Modeling
  • 06:36Conclusion

Summary

Automatic Translation

Automatic Translation

The protocol develops a three-dimensional (3D) model of a dendritic segment with dendritic spines for modeling synaptic plasticity. The constructed mesh can be used for computational modeling of AMPA receptor trafficking in the long-term synaptic plasticity using the software program Blender with CellBlender and MCell.

Tags

3D ModelingDendritic SpinesSynaptic PlasticityComputational ModelingMesh GenerationBlenderCellBlenderSpine HeadSpine NeckCylinderDendrite

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