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Pentylenetetrazole-Induced Kindling Mouse Model
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Neuroscience
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JoVE Journal Neuroscience
Pentylenetetrazole-Induced Kindling Mouse Model

Pentylenetetrazole-Induced Kindling Mouse Model

English

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31,230 Views

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07:06 min

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June 12, 2018

DOI:

10.3791/56573-v

DOI:
10.3791/56573-v

•

07:06 min
June 12, 2018

•

44 Views
,
1Synaptic Plasticity Project,Tokyo Metropolitan Institute of Medical Science

Summary

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This protocol describes a method of chemical kindling with pentylenetetrazole and provides a mouse model of epilepsy. This protocol can also be used to investigate vulnerability to seizure induction and pathogenesis after epileptic seizures in mice.

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Cite this Article

Shimada, T., Yamagata, K. Pentylenetetrazole-Induced Kindling Mouse Model. J. Vis. Exp. (136), e56573, doi:10.3791/56573 (2018).

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