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Inducible and Reversible Dominant-negative (DN) Protein Inhibition
JoVE Journal
Genetics
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JoVE Journal Genetics
Inducible and Reversible Dominant-negative (DN) Protein Inhibition

Inducible and Reversible Dominant-negative (DN) Protein Inhibition

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08:35 min

January 07, 2019

DOI:

08:35 min
January 07, 2019

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Summary

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Here we present a protocol to develop a dominant-negative inducible system, in which any protein can be conditionally inactivated by reversibly overexpressing a dominant-negative mutant version of it.

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