We present a setup of optical tweezers coupled to a light sheet microscope, and its implementation to probe cell mechanics without beads in the Drosophila embryo.
Chardès, C., Clement, R., Blanc, O., Lenne, P. Probing Cell Mechanics with Bead-Free Optical Tweezers in the Drosophila Embryo. J. Vis. Exp. (141), e57900, doi:10.3791/57900 (2018).