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Orthotopic insan Glioblastoma Multiforme Xenografts fare modelleri sitotoksik bağışıklık hücrelerinin stereotaksik evlat edinen Transfer
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Immunology and Infection
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JoVE Journal Immunology and Infection
Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts
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Orthotopic insan Glioblastoma Multiforme Xenografts fare modelleri sitotoksik bağışıklık hücrelerinin stereotaksik evlat edinen Transfer

Türkçe

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7,607 Views

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11:15 min

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September 01, 2018

DOI:

10.3791/57870-v

DOI:
10.3791/57870-v

•

11:15 min
September 01, 2018

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4 Views
, , , , ,
1INSERM, CNRS, Université d’Angers, Université de Nantes,CRCINA, 2Immunotherapy, Graft, Oncology,LabEx IGO, 3Hopital de Nantes,Hotel Dieu

Summary

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Burada, orthotopic insan birincil beyin tümörü taşıyan immünyetmezligi farelerde hazırlık ve allojenik insan lenfosit stereotaksik yönetim için bir iletişim kuralı mevcut. Bu çalışmada bir kanıtı-of-concept fizibilite ve hücresel immunotherapies intrabrain teslim antitümör etkinliği için sağlar.

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Glioblastoma MultiformeCellular ImmunotherapyCytotoxic Immune CellsOrthotopic XenograftsStereotactic InjectionGBM-reactive Effector CellsNSG Mouse ModelTumor MicroenvironmentAdoptive Cell Transfer

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Cite this Article

Jarry, U., Joalland, N., Chauvin, C., Clemenceau, B., Pecqueur, C., Scotet, E. Stereotactic Adoptive Transfer of Cytotoxic Immune Cells in Murine Models of Orthotopic Human Glioblastoma Multiforme Xenografts. J. Vis. Exp. (139), e57870, doi:10.3791/57870 (2018).

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