Journal
/
Neuroscience
/
Γ-アミノ酪酸受容体をモジュレート新規化合物の探索の方法を入力、神経伝達
JoVE Journal
Neuroscience
This content is Free Access.
JoVE Journal Neuroscience
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
Please note that all translations are automatically generated. Click here for the English version.

Γ-アミノ酪酸受容体をモジュレート新規化合物の探索の方法を入力、神経伝達

日本語

Automatically Generated

13,301 Views

•

07:16 min

•

August 16, 2018

DOI:

10.3791/57842-v

DOI:
10.3791/57842-v

•

07:16 min
August 16, 2018

•

7 Views
, ,
1Discovery Neuroscience, Pharma Research and Early Development,Roche Innovation Center Basel, 2HiQScreen Sàrl 6

Summary

Automatically generated

ここでは、生理・薬理のバインドからの GABAAの受容器のアクティブな化合物を発見するためのプロトコルを提案する.

Explore More Videos

GABA-A ReceptorRadioligand BindingElectrophysiologyXenopus OocytesRodent Brain SlicesCompound ScreeningSubtype SelectivityEfficacyMicroinjectionVoltage ClampPopulation Spike RecordingHippocampus

Read Article

Cite this Article

Knoflach, F., Hernandez, M., Bertrand, D. Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. J. Vis. Exp. (138), e57842, doi:10.3791/57842 (2018).

Download .ris file

Copy

Share Video

.

Copy