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Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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JoVE Journal Nörobilim
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

13,300 Views

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07:16 min

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August 16, 2018

DOI:

10.3791/57842-v

DOI:
10.3791/57842-v

•

07:16 min
August 16, 2018

•

7 Views
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1Discovery Neuroscience, Pharma Research and Early Development,Roche Innovation Center Basel, 2HiQScreen Sàrl 6

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Here, we present protocols to discover compounds active at GABAA receptors, from the binding to the physiology and pharmacology.

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Knoflach, F., Hernandez, M., Bertrand, D. Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. J. Vis. Exp. (138), e57842, doi:10.3791/57842 (2018).

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