ジャーナル
/
神経科学
/
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
JoVE Journal
神経科学
This content is Free Access.
JoVE Journal 神経科学
Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission

13,300 Views

•

07:16 min

•

August 16, 2018

DOI:

10.3791/57842-v

DOI:
10.3791/57842-v

•

07:16 min
August 16, 2018

•

7 Views
, ,
1Discovery Neuroscience, Pharma Research and Early Development,Roche Innovation Center Basel, 2HiQScreen Sàrl 6

概要

Automatically generated

Here, we present protocols to discover compounds active at GABAA receptors, from the binding to the physiology and pharmacology.

Explore More Videos

GABA-A ReceptorRadioligand Binding電気生理学Xenopus OocytesRodent Brain SlicesCompound ScreeningSubtype SelectivityEfficacyMicroinjectionVoltage ClampPopulation Spike RecordingHippocampus

Read Article

Cite this Article

Knoflach, F., Hernandez, M., Bertrand, D. Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission. J. Vis. Exp. (138), e57842, doi:10.3791/57842 (2018).

Download .ris file

Copy

Share Video

.

Copy