Journal
/
Genetics
/
Canalostomy als een chirurgische benadering van lokale Drug Delivery tot de Inner oren van volwassen en neonatale muizen
JoVE Journal
Genetics
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Genetics
Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice
Please note that all translations are automatically generated. Click here for the English version.

Canalostomy als een chirurgische benadering van lokale Drug Delivery tot de Inner oren van volwassen en neonatale muizen

Nederlands

Automatically Generated

10,215 Views

•

09:34 min

•

May 25, 2018

DOI:

10.3791/57351-v

DOI:
10.3791/57351-v

•

09:34 min
May 25, 2018

•

22 Views
, , , , , ,
1Department of Otolaryngology-Head and Neck Surgery, Beijing Friendship Hospital,Capital Medical University, 2Department of Otolaryngology-Head and Neck Surgery, Shanghai First People’s Hospital,Shanghai Jiao Tong University

Summary

Automatically generated

Hier beschrijven we canalostomy procedure waarmee lokale drug levering tot de inner oren van volwassen en neonatale muizen door het semicircular kanaal met minimale schade aan gehoorbescherming en vestibulaire functie. Deze methode kan worden gebruikt om te enten virale vectoren, farmaceutische producten en kleine moleculen in het binnenoor muis.

Explore More Videos

CanalostomyInner Ear Drug DeliveryAdult MiceNeonatal MiceSurgical TechniquePolyimide TubingPolyethylene TubingInjection CannulaFast Green DyeAAV8-GFPStreptomycinMicroinjection PumpPostauricular IncisionSemicircular Canal

Read Article

Cite this Article

Guo, J., He, L., Qu, T., Liu, Y., Liu, K., Wang, G., Gong, S. Canalostomy As a Surgical Approach to Local Drug Delivery into the Inner Ears of Adult and Neonatal Mice. J. Vis. Exp. (135), e57351, doi:10.3791/57351 (2018).

Download .ris file

Copy

Share Video

.

Copy