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马达加斯加嘘声蟑螂作为非哺乳动物的替代动物模型来研究毒力、致病机制和药效
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Immunology and Infection
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JoVE Journal Immunology and Infection
The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy
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马达加斯加嘘声蟑螂作为非哺乳动物的替代动物模型来研究毒力、致病机制和药效

DOI:
10.3791/56491-v

•

12:21 min

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November 24, 2017

•

, , , ,
1Bacteriology Division,United States Army Medical Research Institute of Infectious Diseases, 2Southern Research, 3Headquarters Division,United States Army Medical Research Institute of Infectious Diseases

Chapters

  • 00:05Title
  • 02:08Cockroach Preparation for Experimentation
  • 02:58Bacterial Culture and Drug Preparations
  • 05:06Assembly of the Injector
  • 06:15Cockroach Injections
  • 09:22Results: Pathogenic and Virulence Responses in Hissing Cockroaches
  • 10:57Conclusion

Summary

Automatic Translation

Automatic Translation

我们提出了一项协议, 利用马达加斯加嘶咝蟑螂作为替代哺乳动物模型, 以进行细菌的毒力, 发病机制, 药物毒性, 药物功效, 和先天免疫反应研究。

Tags

Madagascar Hissing CockroachAnimal ModelGromphadorhinaMicrobiologyHost-pathogen InteractionsMicrobial PathogenesisVirulence FactorsDrug EfficacyBurkholderiaGalleria WaxwormTemperature AcclimationInjection Procedure

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