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The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy
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Immunology and Infection
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JoVE Journal Immunology and Infection
The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy

The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy

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10,738 Views

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12:21 min

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November 24, 2017

DOI:

10.3791/56491-v

DOI:
10.3791/56491-v

•

12:21 min
November 24, 2017

•

3 Views
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1Bacteriology Division,United States Army Medical Research Institute of Infectious Diseases, 2Southern Research, 3Headquarters Division,United States Army Medical Research Institute of Infectious Diseases

Summary

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We present a protocol to utilize the Madagascar hissing cockroach as an alternative non-mammalian animal model to conduct bacterial virulence, pathogenesis, drug toxicity, drug efficacy, and innate immune response studies.

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Chua, J., Fisher, N. A., Falcinelli, S. D., DeShazer, D., Friedlander, A. M. The Madagascar Hissing Cockroach as an Alternative Non-mammalian Animal Model to Investigate Virulence, Pathogenesis, and Drug Efficacy. J. Vis. Exp. (129), e56491, doi:10.3791/56491 (2017).

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