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A infusão subcutânea de neurotrofina 4 com bombas osmóticas ou injeção muscular direta melhora o envelhecimento dos músculos da laringe do rato
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Developmental Biology
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JoVE Journal Developmental Biology
Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles

A infusão subcutânea de neurotrofina 4 com bombas osmóticas ou injeção muscular direta melhora o envelhecimento dos músculos da laringe do rato

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8,246 Views

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05:50 min

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June 13, 2017

DOI:

10.3791/55837-v

DOI:
10.3791/55837-v

•

05:50 min
June 13, 2017

•

2 Views
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1Department of Rehabilitation Sciences,University of Kentucky, 2Department of Physiology,University of Kentucky

Summary

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Aqui, apresentamos um protocolo para descrever o uso de neurotrofina 4 (NTF4) sistematicamente e diretamente para remodelar os músculos laríngeos do envelhecimento do rato.

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SubcutaneousNeurotrophin 4Osmotic PumpsMuscular InjectionAgingLaryngeal MusclesVocal FunctionMuscle RemodelingMuscle AtrophyOtolaryngologySurgical ProcedureAseptic TechniqueAnesthesiaRat Model

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Cite this Article

Andreatta, R. D., Stemple, J. C., Seward, T. S., McMullen, C. A. Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles. J. Vis. Exp. (124), e55837, doi:10.3791/55837 (2017).

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