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Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles
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Entwicklungsbiologie
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JoVE Journal Entwicklungsbiologie
Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles

Subcutaneous Neurotrophin 4 Infusion Using Osmotic Pumps or Direct Muscular Injection Enhances Aging Rat Laryngeal Muscles

DOI:
10.3791/55837-v

•

05:50 min

•

June 13, 2017

•

, , ,
1Department of Rehabilitation Sciences,University of Kentucky, 2Department of Physiology,University of Kentucky

Kapitel

  • 00:05Titel
  • 01:10Osmotic Pump Implantation
  • 02:49Direct Neurotrophin 4 (NTF4) Injection and Visualization
  • 04:42Results: Representative Effects of NTF4 Administration on Rat Laryngeal Muscle Fiber Size, Innervation, and Neuromuscular Junction Formation
  • 05:09Conclusion

Summary

Automatische Übersetzung

Automatische Übersetzung

Here, we present a protocol to describe the use of neurotrophin 4 (NTF4) systemically and directly to remodel rat aging laryngeal muscles.

Tags

SubcutaneousNeurotrophin 4Osmotic PumpsMuscular InjectionAgingLaryngeal MusclesVocal FunctionMuscle RemodelingMuscle AtrophyOtolaryngologySurgical ProcedureAseptic TechniqueAnesthesiaRat Model

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