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Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish
JoVE Journal
Developmental Biology
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JoVE Journal Developmental Biology
Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish

Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish

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09:53 min

June 03, 2017

DOI:

09:53 min
June 03, 2017

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Summary

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This work presents a new in vivo model of segmental kidney injury using kidney GFP transgenic zebrafish. The model allows for the induction of the targeted ablation of kidney epithelial cells to show the cellular mechanisms of nephron injury and repair.

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