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Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish
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Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish
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June 03, 2017
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This work presents a new in vivo model of segmental kidney injury using kidney GFP transgenic zebrafish. The model allows for the induction of the targeted ablation of kidney epithelial cells to show the cellular mechanisms of nephron injury and repair.
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Datta, R., Wong, A., Camarata, T., Tamanna, F., Ilahi, I., Vasilyev, A. Precise Cellular Ablation Approach for Modeling Acute Kidney Injury in Developing Zebrafish. J. Vis. Exp. (124), e55606, doi:10.3791/55606 (2017).
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