/
/
A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
A subscription to JoVE is required to view this content. Sign in or start your free trial.
8,728 Views
•
09:57 min
•
December 23, 2016
DOI:
Summary
Automatically generated
To deliver cancer drugs to tumor sites with high specificity and reduced side effects, new methods based on nanoparticles are required. Here, we describe disulfide cross-linked micelles that can be easily prepared by hydrogen peroxide-mediated oxidation and are able to dissociate efficiently under a reducing tumor environment to release payloads.
Read Article
Cite this Article
Li, Y., Bharadwaj, G., Lee, J. S. A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles. J. Vis. Exp. (118), e54722, doi:10.3791/54722 (2016).
Copy