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A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles
JoVE Journal
Bioquímica
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JoVE Journal Bioquímica
A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

A Facile and Efficient Approach for the Production of Reversible Disulfide Cross-linked Micelles

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09:57 min

December 23, 2016

DOI:

09:57 min
December 23, 2016

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Summary

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To deliver cancer drugs to tumor sites with high specificity and reduced side effects, new methods based on nanoparticles are required. Here, we describe disulfide cross-linked micelles that can be easily prepared by hydrogen peroxide-mediated oxidation and are able to dissociate efficiently under a reducing tumor environment to release payloads.

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