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Automatische Acoustic Verzicht für die serielle Verdünnung von Peptid-Agonisten im Potency Bestimmung Assays
JoVE Journal
Biochemistry
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JoVE Journal Biochemistry
Automated Acoustic Dispensing for the Serial Dilution of Peptide Agonists in Potency Determination Assays

Automatische Acoustic Verzicht für die serielle Verdünnung von Peptid-Agonisten im Potency Bestimmung Assays

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08:06 min

November 10, 2016

DOI:

08:06 min
November 10, 2016

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Summary

Automatically generated

Peptide adsorption to plasticware during traditional tip-based serial dilutions can significantly impact potency determination and confound the understanding of structure-activity relationships used for lead identification and lead optimization phases of drug discovery. Here methods for automated acoustic non-contact serial dilution of peptide samples are described.

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