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Echtzeit-Impedanz-basierte Zellanalyse als Werkzeug, um molekulare Signalwege in Neurotoxizität und Neuroprotektion in einem neuronalen Zelllinie; Delineate
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Chapters
- 00:05Title
- 01:39Plating and Proliferation of SK-N-SH Cells
- 03:59Serum Deprivation
- 05:04Data Analysis
- 06:11Results: Representative Neurotoxicity/Neuroprotection Data
- 07:53Conclusion
Improved in vitro neurotoxicity assays would aid the identification of new neuroprotective compounds. The utility of a real-time impedance-based cell analyzer to determine cytotoxicity and cytoprotection in neuronal cell lines and to delineate the involvement of second messenger pathways, thus gaining insight in the mechanism of neuroprotection is presented.
