/
/
Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line
A subscription to JoVE is required to view this content. Sign in or start your free trial.
11,320 Views
•
08:23 min
•
August 09, 2014
DOI:
Summary
Automatically generated
Improved in vitro neurotoxicity assays would aid the identification of new neuroprotective compounds. The utility of a real-time impedance-based cell analyzer to determine cytotoxicity and cytoprotection in neuronal cell lines and to delineate the involvement of second messenger pathways, thus gaining insight in the mechanism of neuroprotection is presented.
Read Article
Cite this Article
Marinova, Z., Walitza, S., Grünblatt, E. Real-Time Impedance-based Cell Analyzer as a Tool to Delineate Molecular Pathways Involved in Neurotoxicity and Neuroprotection in a Neuronal Cell Line. J. Vis. Exp. (90), e51748, doi:10.3791/51748 (2014).
Copy