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BLT人性化的鼠标使用一个基于干细胞的基因治疗肿瘤模型的建立
JoVE Journal
Immunology and Infection
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JoVE Journal Immunology and Infection
Using the BLT Humanized Mouse as a Stem Cell based Gene Therapy Tumor Model
DOI:

06:59 min

December 18, 2012

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Chapters

  • 00:05Title
  • 01:26Tissue Transplantation
  • 05:27Results: PET Imaging Is a More Sensitive and Accurate Way to Assess Tumor Regression and Clearance
  • 06:41Conclusion

Summary

Automatic Translation

这里描述的是使用人源化小鼠的肿瘤特异性T细胞的产生和表征。人胸腺组织和转基因的人类造血干细胞移植到免疫功能低下小鼠。这将导致在一个精心设计的人体免疫系统在体内的抗肿瘤免疫反应的检查允许的重组。

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