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May 15, 2012
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Die effiziente Festphasen-Peptid-Synthese eines funktionalisierten Bis-Peptid Trimer Verwendung eines "Safety-catch" Spaltung Verfahren aus HMBA Harz beschrieben.
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Solid-phase SynthesisFunctionalized Bis-peptideSafety Catch MethodologyR.B. MerrifieldSolid SupportProtecting GroupsCoupling MethodsBoc-based ProtectionBase/nucleophile Cleavable Resin StrategyFmoc-based ProtectionAcidic Cleavable Resin StrategyPeptidesBoc/tert-butyl Solid-phase Synthesis StrategyBis-peptide LibrariesCleavage StageDiketopiperazine Formation
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Pfeiffer, C. T., Schafmeister, C. E. Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology. J. Vis. Exp. (63), e4112, doi:10.3791/4112 (2012).
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