This content is Free Access.
24,181 Views
•
11:42 min
•
May 15, 2012
DOI:
Summary
Automatically generated
La synthèse peptidique en phase solide efficace d'un peptide bis-fonctionnalisé trimère utilisant un "cran de sûreté" procédure de clivage de la résine HMBA est décrite.
Explore More Videos
Solid-phase SynthesisFunctionalized Bis-peptideSafety Catch MethodologyR.B. MerrifieldSolid SupportProtecting GroupsCoupling MethodsBoc-based ProtectionBase/nucleophile Cleavable Resin StrategyFmoc-based ProtectionAcidic Cleavable Resin StrategyPeptidesBoc/tert-butyl Solid-phase Synthesis StrategyBis-peptide LibrariesCleavage StageDiketopiperazine Formation
Read Article
Cite this Article
Pfeiffer, C. T., Schafmeister, C. E. Solid Phase Synthesis of a Functionalized Bis-Peptide Using "Safety Catch" Methodology. J. Vis. Exp. (63), e4112, doi:10.3791/4112 (2012).
Copy