/
/
Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
Bu içeriği görüntülemek için JoVE aboneliği gereklidir. Oturum açın veya ücretsiz deneme sürümünü başlatın.
Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
1,312 Views
•
08:16 min
•
July 21, 2022
DOI:
Özet
Automatically generated
Influenza A virus (IAV) infection activates the caspases that cleave host and viral proteins, which, in turn, have pro- and antiviral functions. By employing inhibitors, RNA interference, site-directed mutagenesis, and western blotting and RT-qPCR techniques, caspases in infected mammalian cells that cleave host cortactin and histone deacetylases were identified.
Read Article
Cite this Article
Husain, M. Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection. J. Vis. Exp. (185), e64189, doi:10.3791/64189 (2022).
Copy