Journal
/
/
Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
JoVE Journal
Imunologia e Infecção
Author Produced
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Imunologia e Infecção
Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection

Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection

1,315 Views

08:16 min

July 21, 2022

DOI:

08:16 min
July 21, 2022

5 Views

Summary

Automatically generated

Influenza A virus (IAV) infection activates the caspases that cleave host and viral proteins, which, in turn, have pro- and antiviral functions. By employing inhibitors, RNA interference, site-directed mutagenesis, and western blotting and RT-qPCR techniques, caspases in infected mammalian cells that cleave host cortactin and histone deacetylases were identified.

Read Article