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Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
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Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
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08:16 min
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July 21, 2022
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Influenza A virus (IAV) infection activates the caspases that cleave host and viral proteins, which, in turn, have pro- and antiviral functions. By employing inhibitors, RNA interference, site-directed mutagenesis, and western blotting and RT-qPCR techniques, caspases in infected mammalian cells that cleave host cortactin and histone deacetylases were identified.
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Husain, M. Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection. J. Vis. Exp. (185), e64189, doi:10.3791/64189 (2022).
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