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Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection
JoVE Journal
免疫学と感染
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JoVE Journal 免疫学と感染
Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection

Identifying Caspases and their Motifs that Cleave Proteins During Influenza A Virus Infection

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08:16 min

July 21, 2022

DOI:

08:16 min
July 21, 2022

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概要

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Influenza A virus (IAV) infection activates the caspases that cleave host and viral proteins, which, in turn, have pro- and antiviral functions. By employing inhibitors, RNA interference, site-directed mutagenesis, and western blotting and RT-qPCR techniques, caspases in infected mammalian cells that cleave host cortactin and histone deacetylases were identified.

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