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-Cefoperazone behandelde muismodel van klinisch relevante<em> Clostridium difficile</em> Strain R20291
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JoVE Journal İmmünoloji ve Enfeksiyon
Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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-Cefoperazone behandelde muismodel van klinisch relevante<em> Clostridium difficile</em> Strain R20291

12,056 Views

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06:51 min

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December 10, 2016

DOI:

10.3791/54850-v

DOI:
10.3791/54850-v

•

06:51 min
December 10, 2016

•

5 Views
, , ,
1Department of Population Health and Pathobiology,North Carolina State University College of Veterinary Medicine, 2Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center,University of North Carolina School of Medicine

Özet

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Dit protocol beschrijft de cefoperazon muismodel van Clostridium difficile infectie (CDI) met een klinisch relevante en genetisch handelbaar stam, R20291. Nadruk op klinische ziekte monitoring, C. difficile bacteriële opsomming, toxine cytotoxiciteit en histopathologische veranderingen in heel CDI in een muismodel worden beschreven in het protocol.

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Cite this Article

Winston, J. A., Thanissery, R., Montgomery, S. A., Theriot, C. M. Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291. J. Vis. Exp. (118), e54850, doi:10.3791/54850 (2016).

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