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Cefoperazone שטופל עכבר דגם של קליני רלוונטי<em> Clostridium difficile</em> R20291 הזנים
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JoVE Journal İmmünoloji ve Enfeksiyon
Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291
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Cefoperazone שטופל עכבר דגם של קליני רלוונטי<em> Clostridium difficile</em> R20291 הזנים

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06:51 min

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December 10, 2016

DOI:

10.3791/54850-v

DOI:
10.3791/54850-v

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06:51 min
December 10, 2016

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5 Views
, , ,
1Department of Population Health and Pathobiology,North Carolina State University College of Veterinary Medicine, 2Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center,University of North Carolina School of Medicine

Özet

Automatically generated

פרוטוקול זה מתאר את מודל עכבר cefoperazone של זיהום difficile Clostridium (CDI) באמצעות זן קליני רלוונטי וגנטי-צייתן, R20291. דגש על ניטור מחלה קליני, פקידת חיידקי C. difficile, cytotoxicity רעלן, ושינויי histopathological ברחבי CDI במודל של עכברים מפורטים בפרוטוקול.

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Cite this Article

Winston, J. A., Thanissery, R., Montgomery, S. A., Theriot, C. M. Cefoperazone-treated Mouse Model of Clinically-relevant Clostridium difficile Strain R20291. J. Vis. Exp. (118), e54850, doi:10.3791/54850 (2016).

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