Journal
/
/
Mouse In Vivo Placental Targeted CRISPR Manipulation
JoVE Journal
Genética
É necessária uma assinatura da JoVE para visualizar este conteúdo.  Faça login ou comece sua avaliação gratuita.
JoVE Journal Genética
Mouse In Vivo Placental Targeted CRISPR Manipulation

Mouse In Vivo Placental Targeted CRISPR Manipulation

1,954 Views

07:39 min

April 14, 2023

DOI:

07:39 min
April 14, 2023

10 Views
, ,

Summary

Automatically generated

Here we describe a time-specific method to effectively manipulate critical developmental pathways in the mouse placenta in vivo. This is performed through the injection and electroporation of CRISPR plasmids into the placentas of pregnant dams on embryonic day 12.5.

Read Article