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Mouse In Vivo Placental Targeted CRISPR Manipulation
JoVE 杂志
遗传学
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JoVE 杂志 遗传学
Mouse In Vivo Placental Targeted CRISPR Manipulation

Mouse In Vivo Placental Targeted CRISPR Manipulation

1,954 Views

07:39 min

April 14, 2023

DOI:

07:39 min
April 14, 2023

10 Views
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Summary

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Here we describe a time-specific method to effectively manipulate critical developmental pathways in the mouse placenta in vivo. This is performed through the injection and electroporation of CRISPR plasmids into the placentas of pregnant dams on embryonic day 12.5.

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