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Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
JoVE Journal
Imunologia e Infecção
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JoVE Journal Imunologia e Infecção
Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

Xenograft Skin Model to Manipulate Human Immune Responses In Vivo

2,589 Views

08:23 min

June 29, 2022

DOI:

08:23 min
June 29, 2022

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Summary

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The present protocol describes how to graft human skin onto non-obese diabetic (NOD)-scid interleukin-2 gamma chain receptor (NSG) mice. A detailed description of the preparation of human skin for transplant, preparation of mice for transplant, transplantation of split-thickness human skin, and post-transplantation recovery procedure are included in the report.

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