/
/
Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
Un abonnement à JoVE est nécessaire pour voir ce contenu. Connectez-vous ou commencez votre essai gratuit.
Xenograft Skin Model to Manipulate Human Immune Responses In Vivo
2,569 Views
•
08:23 min
•
June 29, 2022
DOI:
Summary
Automatically generated
The present protocol describes how to graft human skin onto non-obese diabetic (NOD)-scid interleukin-2 gamma chain receptor (NSG) mice. A detailed description of the preparation of human skin for transplant, preparation of mice for transplant, transplantation of split-thickness human skin, and post-transplantation recovery procedure are included in the report.
Read Article
Cite this Article
Moss, M. I., Pauli, M., Moreau, J. M., Cohen, J. N., Rosenblum, M. D., Lowe, M. M. Xenograft Skin Model to Manipulate Human Immune Responses In Vivo. J. Vis. Exp. (184), e64040, doi:10.3791/64040 (2022).
Copy