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猫大型动物模型中人类胚胎干细胞来源的视网膜组织的视网膜下移植
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Neurociência
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JoVE Journal Neurociência
Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model
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猫大型动物模型中人类胚胎干细胞来源的视网膜组织的视网膜下移植

DOI:
10.3791/61683-v

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07:43 min

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August 05, 2021

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, , , , ,
1College of Veterinary Medicine, Department of Small Animal Clinical Sciences,Michigan State University, 2Lineage Cell Therapeutics, Inc.

Capítulos

  • 00:04Introduction
  • 00:51Subretinal Space Preparation
  • 04:50Subretinal Organoid Implantation
  • 06:06Results: Representative Subretinal Organoid Implantation
  • 07:04Conclusion

Summary

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这里介绍的是一种将人多能干细胞（hPSC）衍生的视网膜组织移植到大型动物模型的视网膜下空间的手术技术。

Tags

Subretinal TransplantationFeline Large Animal ModelRetinal DegenerationAge-related Macular DegenerationRetinitis PigmentosaLeber Congenital AmaurosisLateral CanthotomyBarraquer Eyelid SpeculumCastroviejo Corneal Tying ForcepsMosquito HemostatSilk SuturesTenon’s CapsuleSclerotomyPolyglactin Sutures

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