Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model

Laurence  M. Occelli; Felipe Marinho; Ratnesh  K. Singh; Francois Binette; Igor  O. Nasonkin; Simon M. Petersen-Jones

doi:10.3791/61683

Journal

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Neuroscience

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Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model

1,775 Views

•

07:43 min

•

August 05, 2021

DOI:

10.3791/61683-v

DOI:

10.3791/61683-v

•

07:43 min

August 05, 2021

•

5 Views

Laurence M. Occelli*¹, Felipe Marinho*¹, Ratnesh K. Singh², Francois Binette², Igor O. Nasonkin², Simon M. Petersen-Jones¹

¹College of Veterinary Medicine, Department of Small Animal Clinical Sciences,Michigan State University, ²Lineage Cell Therapeutics, Inc.

Summary

Presented here is a surgical technique for transplanting human pluripotent stem cell (hPSC)-derived retinal tissue into the subretinal space of a large animal model.

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Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model

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