Presented here is a surgical technique for transplanting human pluripotent stem cell (hPSC)-derived retinal tissue into the subretinal space of a large animal model.
Occelli, L. M., Marinho, F., Singh, R. K., Binette, F., Nasonkin, I. O., Petersen-Jones, S. M. Subretinal Transplantation of Human Embryonic Stem Cell-Derived Retinal Tissue in a Feline Large Animal Model. J. Vis. Exp. (174), e61683, doi:10.3791/61683 (2021).