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Imunologia e Infecção

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ロックされた核酸修飾オリゴヌクレオチドによるトランスフェクションおよび蚊細胞における標的遺伝子の変異

JoVE Journal
Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Transfection and Mutagenesis of Target Genes in Mosquito Cells by Locked Nucleic Acid-modified Oligonucleotides

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ロックされた核酸修飾オリゴヌクレオチドによるトランスフェクションおよび蚊細胞における標的遺伝子の変異

10,279 Views

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07:25 min

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December 26, 2010

DOI:

DOI:

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07:25 min

December 26, 2010

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7 Views

Nazzy Pakpour, Kong Wai Cheung, Lattha Souvannaseng, Jean-Paul Concordet, Shirley Luckhart

¹Department of Medical Microbiology and Immunology,University of California, Davis, ²Département Génétique et Développement, Institut Cochin,Université Paris Descartes

Tags

Transfection Mutagenesis Target Genes Mosquito Cells Locked Nucleic Acid-modified Oligonucleotides Plasmodium Parasites Malaria Genetically Modified Mosquitoes Cell Signaling Pathways Targeted Mutagenesis Gene Targets Homologous Recombination DNA Molecule Stably Transformed Cell Lines Locked Nucleic Acid-modified Oligonucleotides (LNA-ONs)Artificial Single Nucleotide Substitutions

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