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Imunologia e Infecção

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酸修饰的寡核苷酸锁定核酸转染和蚊虫细胞的靶基因突变

JoVE Journal
Imunologia e Infecção

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JoVE Journal Imunologia e Infecção

Transfection and Mutagenesis of Target Genes in Mosquito Cells by Locked Nucleic Acid-modified Oligonucleotides

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酸修饰的寡核苷酸锁定核酸转染和蚊虫细胞的靶基因突变

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07:25 min

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December 26, 2010

DOI:

DOI:

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07:25 min

December 26, 2010

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7 Views

Nazzy Pakpour, Kong Wai Cheung, Lattha Souvannaseng, Jean-Paul Concordet, Shirley Luckhart

¹Department of Medical Microbiology and Immunology,University of California, Davis, ²Département Génétique et Développement, Institut Cochin,Université Paris Descartes

Tags

Transfection Mutagenesis Target Genes Mosquito Cells Locked Nucleic Acid-modified Oligonucleotides Plasmodium Parasites Malaria Genetically Modified Mosquitoes Cell Signaling Pathways Targeted Mutagenesis Gene Targets Homologous Recombination DNA Molecule Stably Transformed Cell Lines Locked Nucleic Acid-modified Oligonucleotides (LNA-ONs)Artificial Single Nucleotide Substitutions

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