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A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials
JoVE 신문
면역학 및 감염병학
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JoVE 신문 면역학 및 감염병학
A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

A Novel Method to Determine the Longitudinal Antibacterial Activity of Drug-Eluting Materials

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06:18 min

March 03, 2023

DOI:

06:18 min
March 03, 2023

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Summary

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Here, we present a protocol to evaluate the antibacterial efficacy of an antibiotic-eluting polymer to simulate prophylactic clinical application by using a commercially available real-time ATP-based luminescent microbial viability assay. This method enables the monitoring of the longitudinal activity of drug-eluting materials and can be widely adapted to test anti-microbial drug delivery platforms.

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