/
/
Therapeutic Evaluation of Fecal Microbiota Transplantation in an Interleukin 10-Deficient Mouse Model
JoVE 비디오를 활용하시려면 도서관을 통한 기관 구독이 필요합니다. 전체 비디오를 보시려면 로그인하거나 무료 트라이얼을 시작하세요.
Chapters
- 00:04Introduction
- 00:51Collection of Fresh Fecal Pellets
- 02:02Preparation of Fecal Suspension
- 02:45Administration of Fecal Suspension by Oral Gavage
- 04:24Results: BNP Up-Regulation and LVEF Down-Regulation Mitigation by FMT
- 05:09Conclusion
The interaction of genetic susceptibility, mucosal immunity, and intestinal microecological environment is involved in the pathogenesis of inflammatory bowel disease (IBD). In this study, we applied fecal microbiota transplantation to IL-10 deficient mice and investigated its impact on colonic inflammation and heart function.
