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An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats
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An Immunological Model for Heterotopic Heart and Cardiac Muscle Cell Transplantation in Rats
Chapters
- 00:04Introduction
- 00:53Heart Explantation and Perfusion
- 03:13Heart Implantation
- 06:24Enzymatic Heart Digestion and Subcutaneous Cardiac Cell Injection
- 08:08Results: Representative Analyses of the Specificity of the Immune Response in Heterotopic Heart Transplant Rejection
- 09:00Conclusion
We describe a model of heterotopic abdominal heart transplantation in rats, implying modifications of current strategies, which lead to a simplified surgical approach. Additionally, we describe a novel rejection model by in-ear injection of vital cardiac muscle cells, allowing further transplant immunological analyses in rats.
