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使用多盐皮下聚乙烯醇海绵植入和外向尾皮肤伤口模型进行急性伤口愈合评估。
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JoVE 신문 면역학 및 감염병학
Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
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使用多盐皮下聚乙烯醇海绵植入和外向尾皮肤伤口模型进行急性伤口愈合评估。

DOI:
10.3791/60653-v

•

09:06 min

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March 25, 2020

•

, , , ,
1Department of Molecular Microbiology & Immunology,Brown University, 2Division of Surgical Research, Department of Surgery,Rhode Island Hospital and The Warren Alpert School of Medicine of Brown University

Chapters

  • 00:05Introduction
  • 00:53Subcutaneous Polyvinyl Alcohol (PVA) Sponge Implantation
  • 03:09PVA Sponge Fluid Isolation
  • 03:58PVA Sponge Cell Isolation
  • 05:33Tail Skin Excision
  • 06:57Results: Representative Assessment of Acute Wound Healing
  • 08:40Conclusion

Summary

자동 번역

자동 번역

这里描述了两个鼠伤愈合模型，一个旨在评估细胞和细胞因子伤口愈合反应，另一个用于量化伤口愈合率。这些方法可用于复杂的疾病模型，如糖尿病，以确定伤口愈合不良的各个方面的机制。

Tags

Wound HealingPVA Sponge ImplantationExcisional Tail Skin WoundCellular And Cytokine KineticsWound ClosureComorbid ConditionsDiabetesPneumoniaC57-Black/6 MouseSubcutaneous PocketPVA Sponge Implantation Procedure

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