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Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.
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Immunology and Infection
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JoVE Journal Immunology and Infection
Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.

English

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7,786 Views

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09:06 min

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March 25, 2020

DOI:

10.3791/60653-v

DOI:
10.3791/60653-v

•

09:06 min
March 25, 2020

•

6 Views
, , , ,
1Department of Molecular Microbiology & Immunology,Brown University, 2Division of Surgical Research, Department of Surgery,Rhode Island Hospital and The Warren Alpert School of Medicine of Brown University

Summary

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Here, two murine wound healing models are described, one designed to assess cellular and cytokine wound healing responses and the other to quantify the rate of wound closure. These methods can be used with complex disease models such as diabetes to determine mechanisms of various aspects of poor wound healing.

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Cite this Article

Crane, M. J., Henry Jr, W. L., Tran, H. L., Albina, J. E., Jamieson, A. M. Assessment of Acute Wound Healing using the Dorsal Subcutaneous Polyvinyl Alcohol Sponge Implantation and Excisional Tail Skin Wound Models.. J. Vis. Exp. (157), e60653, doi:10.3791/60653 (2020).

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